TBP - NRG1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TBP	ENSG00000112592	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III transcription factor activity, sequence-specific DNA binding RNA polymerase II repressing transcription factor binding protein binding transcription factor binding enzyme binding transcription regulatory region DNA binding repressing transcription factor binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly TFIIA-class transcription factor binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly core promoter binding chromatin binding	SPT15 (S. cerevisiae) tbp-1 (C. elegans) Tbp (D. melanogaster)
NRG1	ENSG00000157168	NSCLC	No drugs in record	transcription cofactor activity protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity cytokine activity ErbB-2 class receptor binding integrin binding growth factor activity transmembrane receptor protein tyrosine kinase activator activity receptor tyrosine kinase binding ErbB-3 class receptor binding chemorepellent activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding sequence-specific DNA binding metal ion binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding nucleic acid binding	No GO terms in record