SIM2 - LCK

H. sapiens

SDL interaction

 LCK NOS2 PIK3C2B PTK6 AMHR2 CAMK2G CRYBB1 EPHB4 ITGB7 LTB4R MAP2K7 MAP3K8 MAPK12 MASP2 UBC TK2 ADORA1 BRCA1 SERPINF1 IDH3G MMP15 FXR2 HSP90AA1 MMP3 WHRN NFKBIE APBA1 GRIK5 IRS4 USP42 RYR1 SIM2 SP1 JUN BCL2 SUMO2 FBXW7 YWHAB SRC RELA STAT3 HSPA4 SMAD3 CASP3 BLM BTRC GRB2 YWHAZ CDK1 SYK VCP DDB1 HDAC2 FANCM PTPN11 UBXN7 ATR KRAS PRKDC MAGOH UBE2N

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIM2 ENSG00000159263

No diseases in record

No drugs in record

RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein heterodimerization activity
sim (D. melanogaster)
LCK ENSG00000182866 T-ALL
DASATINIB
PAZOPANIB
glycoprotein binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
protein kinase binding
protein phosphatase binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
ATPase binding
Src64B (D. melanogaster)