ACVR1 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACVR1	ENSG00000115170	DIPG	No drugs in record	protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta receptor activity, type I protein binding ATP binding peptide hormone binding protein homodimerization activity SMAD binding metal ion binding activin binding transforming growth factor beta binding activin receptor activity, type I	sax (D. melanogaster)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)