H. sapiens

SDL interaction


Gene Name Gene ID Diseases Drugs GO terms Orthologs
ACVR1B ENSG00000135503

No diseases in record

No drugs in record

protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein binding
ATP binding
activin receptor activity, type I
ubiquitin protein ligase binding
inhibin binding
SMAD binding
metal ion binding
activin-activated receptor activity
growth factor binding
activin binding
babo (D. melanogaster)
SMAD3 ENSG00000166949 colorectal carcinoma
oral squamous cell carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter proximal region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
collagen binding
beta-catenin binding
transcription factor binding
zinc ion binding
protein kinase binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
chromatin DNA binding
ubiquitin protein ligase binding
enhancer binding
identical protein binding
protein homodimerization activity
ubiquitin binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
co-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
sma-3 (C. elegans)
sma-2 (C. elegans)