RUNX1 - TERT

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
RUNX1 ENSG00000159216 AML
pre B-ALL
T-ALL

No drugs in record

regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
ATP binding
rnt-1 (C. elegans)
run (D. melanogaster)
lz (D. melanogaster)
TERT ENSG00000164362 melanoma
glioblastoma
hepatocellular carcinoma
bladder
skin basal cell
skin squamous cell
mesothelioma
medulloblastoma
other tumour types

No drugs in record

tRNA binding
transcription coactivator binding
DNA binding
telomerase activity
telomerase RNA reverse transcriptase activity
RNA binding
RNA-directed DNA polymerase activity
protein binding
nucleotidyltransferase activity
telomeric DNA binding
protein homodimerization activity
metal ion binding
telomerase RNA binding
RNA-directed 5'-3' RNA polymerase activity
EST2 (S. cerevisiae)