SMO - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMO	ENSG00000128602	skin basal cell	VISMODEGIB	G-protein coupled receptor activity patched binding protein binding drug binding Wnt-protein binding Wnt-activated receptor activity transmembrane signaling receptor activity	smo (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)