|
Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
|
POLD1
|
ENSG00000062822
|
CRC
|
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
|
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
|
POL3 (S. cerevisiae)
F10C2.4 (C. elegans)
DNApol-delta (D. melanogaster)
|
|
KRAS
|
ENSG00000133703
|
pancreatic
colorectal
lung
thyroid
AML
other tumour types
|
No drugs in record
|
GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
|
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
|
