PRKACA - PDGFRA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKACA	ENSG00000072062	fibrolamellar hepatocellular carcinoma cortisol secreting adrenal adenoma	No drugs in record	protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding protein kinase A regulatory subunit binding	TPK1 (S. cerevisiae) TPK2 (S. cerevisiae) TPK3 (S. cerevisiae) kin-1 (C. elegans) Pka-C1 (D. melanogaster)
PDGFRA	ENSG00000134853	GIST idiopathic hypereosinophilic syndrome paediatric glioblastoma	BECAPLERMIN LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB SUNITINIB	protein kinase activity transmembrane receptor protein tyrosine kinase activity platelet-derived growth factor alpha-receptor activity vascular endothelial growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding ATP binding vascular endothelial growth factor binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)