ITGAV - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITGAV	ENSG00000138448	large intestine carcinoma	No drugs in record	virus receptor activity fibronectin binding protease binding voltage-gated calcium channel activity protein binding coreceptor activity metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding opsonin binding protein kinase C binding fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding	pat-2 (C. elegans) if (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)