ERBB2 - SHMT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)
SHMT1	ENSG00000176974	No diseases in record	No drugs in record	glycine hydroxymethyltransferase activity protein binding L-allo-threonine aldolase activity amino acid binding pyridoxal phosphate binding identical protein binding protein homodimerization activity serine binding	SHM1 (S. cerevisiae) SHM2 (S. cerevisiae)