ARRB1 - ERBB2

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARRB1	ENSG00000137486	No diseases in record	No drugs in record	enzyme inhibitor activity GTPase activator activity insulin-like growth factor receptor binding protein binding transcription factor binding estrogen receptor binding mitogen-activated protein kinase kinase binding ubiquitin protein ligase binding alpha-1A adrenergic receptor binding alpha-1B adrenergic receptor binding angiotensin receptor binding follicle-stimulating hormone receptor binding V2 vasopressin receptor binding AP-2 adaptor complex binding clathrin adaptor activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process transcription regulatory region DNA binding ion channel binding protein phosphorylated amino acid binding histone acetyltransferase activity	Arr1 (D. melanogaster) krz (D. melanogaster) Arr2 (D. melanogaster)
ERBB2	ENSG00000141736	breast ovarian other tumour types NSCLC gastric	AFATINIB LAPATINIB PERTUZUMAB TRASTUZUMAB TRASTUZUMAB EMTANSINE VANDETANIB	RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity growth factor binding	let-23 (C. elegans) Egfr (D. melanogaster)