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ERBB2 - STAT3
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
ERBB2
ENSG00000141736
breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity
growth factor binding
let-23 (C. elegans)
Egfr (D. melanogaster)
STAT3
ENSG00000168610
T-cell large granular lymphocytic leukaemia
paediatric large granular lymphocytic leukaemia
No drugs in record
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
protein kinase binding
protein phosphatase binding
chromatin DNA binding
CCR5 chemokine receptor binding
glucocorticoid receptor binding
identical protein binding
transcription regulatory region DNA binding
protein dimerization activity
No GO terms in record