BRD4 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRD4	ENSG00000141867	lethal midline carcinoma of young people	No drugs in record	RNA polymerase II core binding p53 binding chromatin binding protein binding lysine-acetylated histone binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)