CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000198952 SMG5 H. sapiens SSL Slorth 0.767659 View
ENSG00000071127 WDR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.767581 View
ENSG00000096746 HNRNPH3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.767536 View
ENSG00000066027 PPP2R5A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.767276 View
ENSG00000135446 CDK4 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.767115 View
ENSG00000135446 CDK4 ENSG00000156587 UBE2L6 H. sapiens SSL Slorth 0.766991 View
ENSG00000135446 CDK4 ENSG00000151748 SAV1 H. sapiens SSL Slorth 0.766322 View
ENSG00000115145 STAM2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.766201 View
ENSG00000135446 CDK4 ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.76571 View
ENSG00000135446 CDK4 ENSG00000204388 HSPA1B H. sapiens SSL Slorth 0.765646 View
ENSG00000135446 CDK4 ENSG00000138081 FBXO11 H. sapiens SSL Slorth 0.765441 View
ENSG00000135446 CDK4 ENSG00000163482 STK36 H. sapiens SSL Slorth 0.765322 View
ENSG00000108312 UBTF ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.764861 View
ENSG00000009335 UBE3C ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.764751 View
ENSG00000135446 CDK4 ENSG00000145632 PLK2 H. sapiens SSL Slorth 0.764701 View
ENSG00000104907 TRMT1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.764691 View
ENSG00000135446 CDK4 ENSG00000188191 PRKAR1B H. sapiens SSL Slorth 0.764103 View
ENSG00000135446 CDK4 ENSG00000152795 HNRNPDL H. sapiens SSL Slorth 0.763932 View
ENSG00000129084 PSMA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.763811 View
ENSG00000135446 CDK4 ENSG00000153234 NR4A2 H. sapiens SSL Slorth 0.763569 View
ENSG00000135446 CDK4 ENSG00000144852 NR1I2 H. sapiens SSL Slorth 0.763464 View
ENSG00000135446 CDK4 ENSG00000139083 ETV6 H. sapiens SSL Slorth 0.763388 View
ENSG00000104884 ERCC2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.763103 View
ENSG00000135446 CDK4 ENSG00000186350 RXRA H. sapiens SSL Slorth 0.762725 View
ENSG00000135446 CDK4 ENSG00000155097 ATP6V1C1 H. sapiens SSL Slorth 0.762563 View
ENSG00000122218 COPA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.76191 View
ENSG00000047410 TPR ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.761672 View
ENSG00000135446 CDK4 ENSG00000186432 KPNA4 H. sapiens SSL Slorth 0.76167 View
ENSG00000112335 SNX3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.761441 View
ENSG00000135446 CDK4 ENSG00000172757 CFL1 H. sapiens SSL Slorth 0.761068 View
ENSG00000122545 SEPT7 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.760608 View
ENSG00000135446 CDK4 ENSG00000136826 KLF4 H. sapiens SSL Slorth 0.760527 View
ENSG00000135446 CDK4 ENSG00000141378 PTRH2 H. sapiens SSL Slorth 0.760416 View
ENSG00000109819 PPARGC1A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.760228 View
ENSG00000135446 CDK4 ENSG00000176444 CLK2 H. sapiens SSL Slorth 0.759504 View
ENSG00000133026 MYH10 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.759495 View
ENSG00000054118 THRAP3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.759241 View
ENSG00000135446 CDK4 ENSG00000168214 RBPJ H. sapiens SSL Slorth 0.759014 View
ENSG00000135446 CDK4 ENSG00000198522 GPN1 H. sapiens SSL Slorth 0.758598 View
ENSG00000135446 CDK4 ENSG00000136352 NKX2-1 H. sapiens SSL Slorth 0.757617 View