ERCC2

ENSG00000104884 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008094 DNA-dependent ATPase activity
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0004672 protein kinase activity
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity

Drugs

No drugs in record

Diseases

Disease Name
skin basal cell
skin squamous cell
melanoma

Orthologs

Gene Organism
RAD3 S. cerevisiae
Y50D7A.11 C. elegans
Xpd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000005339 CREBBP ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.991231 View
ENSG00000104884 ERCC2 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.99087 View
ENSG00000100644 HIF1A ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.989895 View
ENSG00000091831 ESR1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.989268 View
ENSG00000012048 BRCA1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.986891 View
ENSG00000104884 ERCC2 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.98688 View
ENSG00000103275 UBE2I ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.986681 View
ENSG00000104884 ERCC2 ENSG00000170315 UBB H. sapiens SDL Slorth 0.985547 View
ENSG00000104884 ERCC2 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.984674 View
ENSG00000100030 MAPK1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.983269 View
ENSG00000100393 EP300 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.982449 View
ENSG00000104884 ERCC2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.982217 View
ENSG00000080824 HSP90AA1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.980907 View
ENSG00000101266 CSNK2A1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.980842 View
ENSG00000104884 ERCC2 ENSG00000177606 JUN H. sapiens SDL Slorth 0.979928 View
ENSG00000104884 ERCC2 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.979546 View
ENSG00000104884 ERCC2 ENSG00000136997 MYC H. sapiens SDL Slorth 0.979056 View
ENSG00000104884 ERCC2 ENSG00000150991 UBC H. sapiens SDL Slorth 0.978592 View
ENSG00000104884 ERCC2 ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.978558 View
ENSG00000104365 IKBKB ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.977399 View
ENSG00000100906 NFKBIA ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.977159 View
ENSG00000100029 PES1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.977031 View
ENSG00000104884 ERCC2 ENSG00000169083 AR H. sapiens SDL Slorth 0.976762 View
ENSG00000104884 ERCC2 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.976406 View
ENSG00000104884 ERCC2 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.975343 View
ENSG00000097007 ABL1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.973898 View
ENSG00000096384 HSP90AB1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.973799 View
ENSG00000082898 XPO1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.97357 View
ENSG00000104884 ERCC2 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.97285 View
ENSG00000104884 ERCC2 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.972183 View
ENSG00000104884 ERCC2 ENSG00000173039 RELA H. sapiens SDL Slorth 0.972092 View
ENSG00000104884 ERCC2 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.97133 View
ENSG00000101966 XIAP ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.96698 View
ENSG00000104884 ERCC2 ENSG00000140464 PML H. sapiens SDL Slorth 0.966668 View
ENSG00000104884 ERCC2 ENSG00000197122 SRC H. sapiens SDL Slorth 0.96638 View
ENSG00000094916 CBX5 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.965993 View
ENSG00000104884 ERCC2 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.965136 View
ENSG00000104884 ERCC2 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.964369 View
ENSG00000055130 CUL1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.964151 View
ENSG00000104884 ERCC2 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.96205 View