ERCC2 - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERCC2	ENSG00000104884	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity 5'-3' DNA helicase activity metal ion binding protein N-terminus binding 4 iron, 4 sulfur cluster binding protein kinase activity RNA polymerase II carboxy-terminal domain kinase activity	RAD3 (S. cerevisiae) Y50D7A.11 (C. elegans) Xpd (D. melanogaster)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)