SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000166949 SMAD3 ENSG00000167513 CDT1 H. sapiens SDL Slorth 0.991507 View
ENSG00000166949 SMAD3 ENSG00000269858 EGLN2 H. sapiens SDL Slorth 0.991074 View
ENSG00000163513 TGFBR2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.991035 View
ENSG00000166949 SMAD3 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.990752 View
ENSG00000166949 SMAD3 ENSG00000185359 HGS H. sapiens SDL Slorth 0.990627 View
ENSG00000166949 SMAD3 ENSG00000187608 ISG15 H. sapiens SDL Slorth 0.990624 View
ENSG00000166949 SMAD3 ENSG00000178999 AURKB H. sapiens SDL Slorth 0.990376 View
ENSG00000166949 SMAD3 ENSG00000171223 JUNB H. sapiens SDL Slorth 0.989815 View
ENSG00000166949 SMAD3 ENSG00000176105 YES1 H. sapiens SDL Slorth 0.98975 View
ENSG00000166949 SMAD3 ENSG00000189079 ARID2 H. sapiens SDL Slorth 0.989495 View
ENSG00000166949 SMAD3 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.989423 View
ENSG00000166949 SMAD3 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.989384 View
ENSG00000166949 SMAD3 ENSG00000183735 TBK1 H. sapiens SDL Slorth 0.989371 View
ENSG00000063245 EPN1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.989293 View
ENSG00000166949 SMAD3 ENSG00000177731 FLII H. sapiens SDL Slorth 0.989208 View
ENSG00000166949 SMAD3 ENSG00000170242 USP47 H. sapiens SDL Slorth 0.989135 View
ENSG00000166949 SMAD3 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.988848 View
ENSG00000166949 SMAD3 ENSG00000168078 PBK H. sapiens SDL Slorth 0.988681 View
ENSG00000166949 SMAD3 ENSG00000185344 ATP6V0A2 H. sapiens SDL Slorth 0.988613 View
ENSG00000166949 SMAD3 ENSG00000187741 FANCA H. sapiens SDL Slorth 0.988556 View
ENSG00000166949 SMAD3 ENSG00000197157 SND1 H. sapiens SDL Slorth 0.988492 View
ENSG00000166949 SMAD3 ENSG00000169045 HNRNPH1 H. sapiens SDL Slorth 0.988441 View
ENSG00000166949 SMAD3 ENSG00000177105 RHOG H. sapiens SDL Slorth 0.987909 View
ENSG00000166949 SMAD3 ENSG00000204217 BMPR2 H. sapiens SDL Slorth 0.987824 View
ENSG00000166949 SMAD3 ENSG00000221823 PPP3R1 H. sapiens SDL Slorth 0.987765 View
ENSG00000166949 SMAD3 ENSG00000169564 PCBP1 H. sapiens SDL Slorth 0.987647 View
ENSG00000166949 SMAD3 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.987617 View
ENSG00000082781 ITGB5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.987604 View
ENSG00000166949 SMAD3 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.987538 View
ENSG00000166949 SMAD3 ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.987412 View
ENSG00000166949 SMAD3 ENSG00000211455 STK38L H. sapiens SDL Slorth 0.987294 View
ENSG00000166949 SMAD3 ENSG00000169813 HNRNPF H. sapiens SDL Slorth 0.98721 View
ENSG00000166949 SMAD3 ENSG00000196628 TCF4 H. sapiens SDL Slorth 0.987041 View
ENSG00000166949 SMAD3 ENSG00000169750 RAC3 H. sapiens SDL Slorth 0.98703 View
ENSG00000092820 EZR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.986735 View
ENSG00000133703 KRAS ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.986684 View
ENSG00000166949 SMAD3 ENSG00000173846 PLK3 H. sapiens SDL Slorth 0.986594 View
ENSG00000166949 SMAD3 ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.986568 View
ENSG00000120063 GNA13 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.986556 View
ENSG00000166949 SMAD3 ENSG00000198554 WDHD1 H. sapiens SDL Slorth 0.986534 View