RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000133703 KRAS ENSG00000132155 RAF1 H. sapiens SSL BioGRID 2.0 View
ENSG00000213281 NRAS ENSG00000132155 RAF1 H. sapiens SSL BioGRID 1.0 View
ENSG00000132155 RAF1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.990121 View
ENSG00000132155 RAF1 ENSG00000155849 ELMO1 H. sapiens SDL Slorth 0.989986 View
ENSG00000132155 RAF1 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.989251 View
ENSG00000132155 RAF1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.988846 View
ENSG00000132155 RAF1 ENSG00000137265 IRF4 H. sapiens SDL Slorth 0.98869 View
ENSG00000132155 RAF1 ENSG00000158186 MRAS H. sapiens SDL Slorth 0.988541 View
ENSG00000132155 RAF1 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.988434 View
ENSG00000132155 RAF1 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.988395 View
ENSG00000132155 RAF1 ENSG00000269858 EGLN2 H. sapiens SDL Slorth 0.988374 View
ENSG00000132155 RAF1 ENSG00000140022 STON2 H. sapiens SDL Slorth 0.988151 View
ENSG00000132155 RAF1 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.988078 View
ENSG00000132155 RAF1 ENSG00000158022 TRIM63 H. sapiens SDL Slorth 0.987928 View
ENSG00000132155 RAF1 ENSG00000188191 PRKAR1B H. sapiens SDL Slorth 0.98789 View
ENSG00000132155 RAF1 ENSG00000177105 RHOG H. sapiens SDL Slorth 0.987875 View
ENSG00000132155 RAF1 ENSG00000198836 OPA1 H. sapiens SDL Slorth 0.987853 View
ENSG00000132155 RAF1 ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.987723 View
ENSG00000132155 RAF1 ENSG00000135144 DTX1 H. sapiens SDL Slorth 0.987592 View
ENSG00000132155 RAF1 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.987495 View
ENSG00000132155 RAF1 ENSG00000138613 APH1B H. sapiens SDL Slorth 0.987444 View
ENSG00000132155 RAF1 ENSG00000221823 PPP3R1 H. sapiens SDL Slorth 0.987234 View
ENSG00000132155 RAF1 ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.987157 View
ENSG00000132155 RAF1 ENSG00000151694 ADAM17 H. sapiens SDL Slorth 0.987034 View
ENSG00000132155 RAF1 ENSG00000154447 SH3RF1 H. sapiens SDL Slorth 0.986974 View
ENSG00000132155 RAF1 ENSG00000173933 RBM4 H. sapiens SDL Slorth 0.98683 View
ENSG00000132155 RAF1 ENSG00000165806 CASP7 H. sapiens SDL Slorth 0.986807 View
ENSG00000132155 RAF1 ENSG00000141380 SS18 H. sapiens SDL Slorth 0.9867 View
ENSG00000132155 RAF1 ENSG00000133703 KRAS H. sapiens SDL Slorth 0.986672 View
ENSG00000132155 RAF1 ENSG00000155097 ATP6V1C1 H. sapiens SDL Slorth 0.986668 View
ENSG00000132155 RAF1 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.986619 View
ENSG00000132155 RAF1 ENSG00000147010 SH3KBP1 H. sapiens SDL Slorth 0.986574 View
ENSG00000132155 RAF1 ENSG00000213281 NRAS H. sapiens SDL Slorth 0.986479 View
ENSG00000132155 RAF1 ENSG00000142675 CNKSR1 H. sapiens SDL Slorth 0.986446 View
ENSG00000132155 RAF1 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.986416 View
ENSG00000132155 RAF1 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.986416 View
ENSG00000132155 RAF1 ENSG00000140332 TLE3 H. sapiens SDL Slorth 0.98638 View
ENSG00000132155 RAF1 ENSG00000164056 SPRY1 H. sapiens SDL Slorth 0.986274 View
ENSG00000132155 RAF1 ENSG00000156709 AIFM1 H. sapiens SDL Slorth 0.986269 View
ENSG00000132155 RAF1 ENSG00000187098 MITF H. sapiens SDL Slorth 0.986129 View