Go term | Description |
---|---|
GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity |
GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity |
GO:0005515 | protein binding |
GO:0008144 | drug binding |
GO:0019899 | enzyme binding |
GO:0030552 | cAMP binding |
GO:0031698 | beta-2 adrenergic receptor binding |
GO:0044325 | ion channel binding |
GO:0046872 | metal ion binding |
GO:0051117 | ATPase binding |
GO:0097110 | scaffold protein binding |
Drug name | Description |
---|---|
AMLEXANOX | Phosphodiesterase 4 inhibitor |
APREMILAST | Phosphodiesterase 4 inhibitor |
DIPYRIDAMOLE | |
DYPHYLLINE | Phosphodiesterase 4 inhibitor |
FLAVOXATE | Phosphodiesterase 4 inhibitor |
PENTOXIFYLLINE | Adenosine A2 receptor antagonist |
ROFLUMILAST | Phosphodiesterase 4 inhibitor |
THEOPHYLLINE | Adenosine receptor antagonist |
THEOPHYLLINE GLYCINATE | Adenosine receptor antagonist |
No diseases in record
Gene | Organism | |
---|---|---|
pde-4 | C. elegans | |
dnc | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000082701 | GSK3B | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.945519 | View |
ENSG00000097046 | CDC7 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.941765 | View |
ENSG00000108298 | RPL19 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.940782 | View |
ENSG00000100519 | PSMC6 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.940416 | View |
ENSG00000103275 | UBE2I | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.940385 | View |
ENSG00000041357 | PSMA4 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.940306 | View |
ENSG00000008018 | PSMB1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.939772 | View |
ENSG00000103035 | PSMD7 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.939251 | View |
ENSG00000087191 | PSMC5 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.939186 | View |
ENSG00000108671 | PSMD11 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.939044 | View |
ENSG00000072062 | PRKACA | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.936819 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.936214 | View |
ENSG00000106588 | PSMA2 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.934492 | View |
ENSG00000113448 | PDE4D | ENSG00000140464 | PML | H. sapiens | SDL | Slorth | 0.93369 | View |
ENSG00000055130 | CUL1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.932319 | View |
ENSG00000100644 | HIF1A | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.932307 | View |
ENSG00000100030 | MAPK1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.930825 | View |
ENSG00000097007 | ABL1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.930344 | View |
ENSG00000113448 | PDE4D | ENSG00000139687 | RB1 | H. sapiens | SDL | Slorth | 0.929807 | View |
ENSG00000108443 | RPS6KB1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.926817 | View |
ENSG00000113448 | PDE4D | ENSG00000168610 | STAT3 | H. sapiens | SDL | Slorth | 0.925241 | View |
ENSG00000004700 | RECQL | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.925013 | View |
ENSG00000101868 | POLA1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.924773 | View |
ENSG00000112062 | MAPK14 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.922883 | View |
ENSG00000110395 | CBL | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.921662 | View |
ENSG00000010810 | FYN | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.921303 | View |
ENSG00000113448 | PDE4D | ENSG00000185591 | SP1 | H. sapiens | SDL | Slorth | 0.915776 | View |
ENSG00000113448 | PDE4D | ENSG00000196591 | HDAC2 | H. sapiens | SDL | Slorth | 0.914543 | View |
ENSG00000072401 | UBE2D1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.914336 | View |
ENSG00000113448 | PDE4D | ENSG00000221983 | UBA52 | H. sapiens | SDL | Slorth | 0.913369 | View |
ENSG00000105372 | RPS19 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.907388 | View |
ENSG00000105640 | RPL18A | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.901374 | View |
ENSG00000071082 | RPL31 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.901355 | View |
ENSG00000062822 | POLD1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.900817 | View |
ENSG00000104365 | IKBKB | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.895269 | View |
ENSG00000112062 | MAPK14 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.894529 | View |
ENSG00000105810 | CDK6 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.890077 | View |
ENSG00000012048 | BRCA1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.885149 | View |
ENSG00000010810 | FYN | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.884921 | View |
ENSG00000110713 | NUP98 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.880046 | View |