POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000136273 HUS1 ENSG00000101868 POLA1 H. sapiens SSL BioGRID 1.0 View
ENSG00000133703 KRAS ENSG00000101868 POLA1 H. sapiens SSL BioGRID 1.0 View
ENSG00000101868 POLA1 ENSG00000241343 RPL36A H. sapiens SSL BioGRID 1.0 View
ENSG00000101868 POLA1 ENSG00000126261 UBA2 H. sapiens SSL BioGRID 1.0 View
ENSG00000136997 MYC ENSG00000101868 POLA1 H. sapiens SDL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.987431 View
ENSG00000101868 POLA1 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.987002 View
ENSG00000012048 BRCA1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.985007 View
ENSG00000005339 CREBBP ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.984671 View
ENSG00000101266 CSNK2A1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.983798 View
ENSG00000101868 POLA1 ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.982202 View
ENSG00000101868 POLA1 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.978143 View
ENSG00000101868 POLA1 ENSG00000115524 SF3B1 H. sapiens SSL Slorth 0.975713 View
ENSG00000101868 POLA1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.97553 View
ENSG00000101868 POLA1 ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.975141 View
ENSG00000101868 POLA1 ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.974978 View
ENSG00000101868 POLA1 ENSG00000141543 EIF4A3 H. sapiens SSL Slorth 0.974962 View
ENSG00000101868 POLA1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.974878 View
ENSG00000101868 POLA1 ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.974773 View
ENSG00000101868 POLA1 ENSG00000105401 CDC37 H. sapiens SSL Slorth 0.974701 View
ENSG00000080824 HSP90AA1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.974557 View
ENSG00000101868 POLA1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.974521 View
ENSG00000100030 MAPK1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.97431 View
ENSG00000101868 POLA1 ENSG00000159216 RUNX1 H. sapiens SSL Slorth 0.974301 View
ENSG00000093009 CDC45 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.974231 View
ENSG00000101868 POLA1 ENSG00000129559 NEDD8 H. sapiens SSL Slorth 0.974057 View
ENSG00000101868 POLA1 ENSG00000109332 UBE2D3 H. sapiens SSL Slorth 0.974 View
ENSG00000101868 POLA1 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.973987 View
ENSG00000101868 POLA1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.973487 View
ENSG00000101868 POLA1 ENSG00000139343 SNRPF H. sapiens SSL Slorth 0.973475 View
ENSG00000101868 POLA1 ENSG00000131876 SNRPA1 H. sapiens SSL Slorth 0.973431 View
ENSG00000101868 POLA1 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.973404 View
ENSG00000101868 POLA1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.973354 View
ENSG00000101868 POLA1 ENSG00000108883 EFTUD2 H. sapiens SSL Slorth 0.973321 View
ENSG00000101868 POLA1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.97319 View
ENSG00000101868 POLA1 ENSG00000109320 NFKB1 H. sapiens SSL Slorth 0.973106 View
ENSG00000101868 POLA1 ENSG00000144028 SNRNP200 H. sapiens SSL Slorth 0.973093 View
ENSG00000101868 POLA1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.973032 View
ENSG00000087191 PSMC5 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.972872 View
ENSG00000101868 POLA1 ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.972627 View