DHFR

ENSG00000228716 - H. sapiens

Pathways

Go term Description
GO:0003729 mRNA binding
GO:0004146 dihydrofolate reductase activity
GO:0005542 folic acid binding
GO:0008144 drug binding
GO:0033560 folate reductase activity
GO:0051870 methotrexate binding
GO:0070402 NADPH binding
GO:0005515 protein binding
GO:0050661 NADP binding

Drugs

Drug name Description
METHOTREXATE Dihydrofolate reductase inhibitor
PEMETREXED Dihydrofolate reductase inhibitor
PRALATREXATE Dihydrofolate reductase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
DFR1 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000005339 CREBBP ENSG00000228716 DHFR H. sapiens SSL Slorth 0.776455 View
ENSG00000005007 UPF1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.775705 View
ENSG00000105011 ASF1B ENSG00000228716 DHFR H. sapiens SSL Slorth 0.774898 View
ENSG00000141543 EIF4A3 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.771791 View
ENSG00000197122 SRC ENSG00000228716 DHFR H. sapiens SSL Slorth 0.769604 View
ENSG00000101966 XIAP ENSG00000228716 DHFR H. sapiens SSL Slorth 0.766169 View
ENSG00000197299 BLM ENSG00000228716 DHFR H. sapiens SSL Slorth 0.766086 View
ENSG00000169083 AR ENSG00000228716 DHFR H. sapiens SSL Slorth 0.764794 View
ENSG00000091831 ESR1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.764726 View
ENSG00000093009 CDC45 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.763088 View
ENSG00000127022 CANX ENSG00000228716 DHFR H. sapiens SSL Slorth 0.763059 View
ENSG00000157106 SMG1 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.7599 View
ENSG00000196235 SUPT5H ENSG00000228716 DHFR H. sapiens SSL Slorth 0.758621 View
ENSG00000188906 LRRK2 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.757055 View
ENSG00000101811 CSTF2 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.756895 View
ENSG00000036257 CUL3 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.756089 View
ENSG00000141646 SMAD4 ENSG00000228716 DHFR H. sapiens SSL Slorth 0.754262 View
ENSG00000136628 EPRS ENSG00000228716 DHFR H. sapiens SSL Slorth 0.753882 View
ENSG00000100906 NFKBIA ENSG00000228716 DHFR H. sapiens SSL Slorth 0.75119 View