PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000179295 PTPN11 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.984985 View
ENSG00000010671 BTK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.983438 View
ENSG00000134871 COL4A2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.983053 View
ENSG00000138829 FBN2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.983029 View
ENSG00000111540 RAB5B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.982825 View
ENSG00000137942 FNBP1L ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.98282 View
ENSG00000145506 NKD2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981979 View
ENSG00000143847 PPFIA4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981837 View
ENSG00000104140 RHOV ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981666 View
ENSG00000125810 CD93 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981573 View
ENSG00000141503 MINK1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981432 View
ENSG00000146830 GIGYF1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981039 View
ENSG00000041353 RAB27B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.981038 View
ENSG00000178363 CALML3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.980915 View
ENSG00000108830 RND2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.980609 View
ENSG00000137673 MMP7 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.980296 View
ENSG00000139219 COL2A1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.980148 View
ENSG00000128271 ADORA2A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979798 View
ENSG00000168487 BMP1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979784 View
ENSG00000067141 NEO1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979784 View
ENSG00000092421 SEMA6A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979693 View
ENSG00000171126 KCNG3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979693 View
ENSG00000029639 TFB1M ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.979587 View
ENSG00000179295 PTPN11 ENSG00000182511 FES H. sapiens SDL Slorth 0.979553 View
ENSG00000111262 KCNA1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97945 View
ENSG00000179295 PTPN11 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.979235 View
ENSG00000148429 USP6NL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.978943 View
ENSG00000063660 GPC1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.978564 View
ENSG00000134138 MEIS2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.978451 View
ENSG00000134363 FST ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.978244 View
ENSG00000179295 PTPN11 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.978083 View
ENSG00000165240 ATP7A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.978038 View
ENSG00000110148 CCKBR ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977963 View
ENSG00000087510 TFAP2C ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977515 View
ENSG00000148677 ANKRD1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977413 View
ENSG00000140564 FURIN ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977411 View
ENSG00000106327 TFR2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977261 View
ENSG00000166947 EPB42 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977066 View
ENSG00000117400 MPL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.977017 View
ENSG00000179295 PTPN11 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.976942 View