UBA3 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBA3	ENSG00000144744	No diseases in record	No drugs in record	protein binding ATP binding acid-amino acid ligase activity ligand-dependent nuclear receptor binding NEDD8 activating enzyme activity identical protein binding protein heterodimerization activity small protein activating enzyme activity ligase activity nucleotide binding	UBA3 (S. cerevisiae) rfl-1 (C. elegans) Uba3 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)