Go term | Description |
---|---|
GO:0004672 | protein kinase activity |
GO:0004674 | protein serine/threonine kinase activity |
GO:0004709 | MAP kinase kinase kinase activity |
GO:0005509 | calcium ion binding |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0031434 | mitogen-activated protein kinase kinase binding |
GO:0042802 | identical protein binding |
GO:0046982 | protein heterodimerization activity |
GO:0031267 | small GTPase binding |
Drug name | Description |
---|---|
DABRAFENIB | Serine/threonine-protein kinase B-raf inhibitor |
REGORAFENIB | Tyrosine-protein kinase ABL inhibitor |
SORAFENIB | Serine/threonine-protein kinase RAF inhibitor |
VEMURAFENIB | Serine/threonine-protein kinase B-raf inhibitor |
Disease Name |
---|
melanoma |
colorectal |
papillary thyroid |
borderline ovarian |
NSCLC |
cholangiocarcinoma |
pilocytic astrocytoma |
Spitzoid tumour |
pancreas acinar carcinoma |
melanocytic nevus |
prostate |
gastric |
Gene | Organism | |
---|---|---|
lin-45 | C. elegans |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000157764 | BRAF | ENSG00000139618 | BRCA2 | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000146648 | EGFR | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000066468 | FGFR2 | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000168522 | FNTA | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000196591 | HDAC2 | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000169032 | MAP2K1 | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000100030 | MAPK1 | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000121879 | PIK3CA | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000157764 | BRAF | ENSG00000134086 | VHL | H. sapiens | SSL | BioGRID | 1.0 | View |
ENSG00000012048 | BRCA1 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.990686 | View |
ENSG00000005339 | CREBBP | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.988627 | View |
ENSG00000100393 | EP300 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.987463 | View |
ENSG00000150991 | UBC | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.9873 | View |
ENSG00000116478 | HDAC1 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.984791 | View |
ENSG00000136997 | MYC | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.984601 | View |
ENSG00000142208 | AKT1 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.982258 | View |
ENSG00000135446 | CDK4 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.979916 | View |
ENSG00000149554 | CHEK1 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.979856 | View |
ENSG00000101412 | E2F1 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.979059 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.978663 | View |
ENSG00000005339 | CREBBP | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.977978 | View |
ENSG00000121022 | COPS5 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.97788 | View |
ENSG00000112592 | TBP | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.977839 | View |
ENSG00000123374 | CDK2 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.97772 | View |
ENSG00000103275 | UBE2I | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.977562 | View |
ENSG00000141646 | SMAD4 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.977401 | View |
ENSG00000116030 | SUMO1 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.97736 | View |
ENSG00000157764 | BRAF | ENSG00000175387 | SMAD2 | H. sapiens | SSL | Slorth | 0.977306 | View |
ENSG00000012048 | BRCA1 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.977265 | View |
ENSG00000132646 | PCNA | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.976894 | View |
ENSG00000140464 | PML | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.976556 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.976433 | View |
ENSG00000137693 | YAP1 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.976433 | View |
ENSG00000136997 | MYC | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.976197 | View |
ENSG00000109670 | FBXW7 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.975886 | View |
ENSG00000104365 | IKBKB | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.975545 | View |
ENSG00000102882 | MAPK3 | ENSG00000157764 | BRAF | H. sapiens | SDL | Slorth | 0.9755 | View |
ENSG00000157764 | BRAF | ENSG00000159692 | CTBP1 | H. sapiens | SSL | Slorth | 0.975471 | View |
ENSG00000112062 | MAPK14 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.975452 | View |
ENSG00000141736 | ERBB2 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.975229 | View |