BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000155868 MED7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.755871 View
ENSG00000054118 THRAP3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.755673 View
ENSG00000116106 EPHA4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.755118 View
ENSG00000157764 BRAF ENSG00000175662 TOM1L2 H. sapiens SSL Slorth 0.754915 View
ENSG00000101197 BIRC7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.754772 View
ENSG00000157764 BRAF ENSG00000262814 MRPL12 H. sapiens SSL Slorth 0.75424 View
ENSG00000108590 MED31 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.754026 View
ENSG00000101945 SUV39H1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.753651 View
ENSG00000113643 RARS ENSG00000157764 BRAF H. sapiens SSL Slorth 0.752992 View
ENSG00000044115 CTNNA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.7526 View
ENSG00000005249 PRKAR2B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.752216 View
ENSG00000157764 BRAF ENSG00000183454 GRIN2A H. sapiens SSL Slorth 0.752059 View
ENSG00000157764 BRAF ENSG00000163114 PDHA2 H. sapiens SSL Slorth 0.751918 View
ENSG00000157764 BRAF ENSG00000178394 HTR1A H. sapiens SSL Slorth 0.751912 View
ENSG00000157557 ETS2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.751729 View
ENSG00000141378 PTRH2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.751619 View
ENSG00000047410 TPR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.751591 View
ENSG00000111642 CHD4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.751161 View
ENSG00000157764 BRAF ENSG00000163602 RYBP H. sapiens SSL Slorth 0.751151 View
ENSG00000089685 BIRC5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.751135 View
ENSG00000124535 WRNIP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.75108 View
ENSG00000075413 MARK3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.750861 View
ENSG00000101057 MYBL2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.750849 View
ENSG00000055118 KCNH2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.750726 View
ENSG00000082458 DLG3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.750609 View
ENSG00000157764 BRAF ENSG00000168092 PAFAH1B2 H. sapiens SSL Slorth 0.750584 View
ENSG00000157764 BRAF ENSG00000181789 COPG1 H. sapiens SSL Slorth 0.750558 View
ENSG00000157764 BRAF ENSG00000163110 PDLIM5 H. sapiens SSL Slorth 0.750409 View
ENSG00000157764 BRAF ENSG00000266173 STRADA H. sapiens SSL Slorth 0.750189 View
ENSG00000140553 UNC45A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.750032 View