BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000198001 IRAK4 H. sapiens SSL Slorth 0.787516 View
ENSG00000120063 GNA13 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.787267 View
ENSG00000108312 UBTF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.78717 View
ENSG00000104856 RELB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.787149 View
ENSG00000067225 PKM ENSG00000157764 BRAF H. sapiens SSL Slorth 0.787123 View
ENSG00000157764 BRAF ENSG00000178028 DMAP1 H. sapiens SSL Slorth 0.787059 View
ENSG00000143933 CALM2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.786842 View
ENSG00000157764 BRAF ENSG00000169714 CNBP H. sapiens SSL Slorth 0.78669 View
ENSG00000147274 RBMX ENSG00000157764 BRAF H. sapiens SSL Slorth 0.786632 View
ENSG00000014216 CAPN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.78602 View
ENSG00000157764 BRAF ENSG00000165169 DYNLT3 H. sapiens SSL Slorth 0.785878 View
ENSG00000113658 SMAD5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.785844 View
ENSG00000114978 MOB1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.784752 View
ENSG00000100138 SNU13 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.784675 View
ENSG00000157764 BRAF ENSG00000185513 L3MBTL1 H. sapiens SSL Slorth 0.784349 View
ENSG00000134954 ETS1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.784252 View
ENSG00000157764 BRAF ENSG00000188130 MAPK12 H. sapiens SSL Slorth 0.783848 View
ENSG00000065150 IPO5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.783801 View
ENSG00000157764 BRAF ENSG00000164056 SPRY1 H. sapiens SSL Slorth 0.783749 View
ENSG00000157764 BRAF ENSG00000166477 LEO1 H. sapiens SSL Slorth 0.783379 View
ENSG00000157764 BRAF ENSG00000180176 TH H. sapiens SSL Slorth 0.78335 View
ENSG00000074800 ENO1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.783047 View
ENSG00000157764 BRAF ENSG00000185532 PRKG1 H. sapiens SSL Slorth 0.782883 View
ENSG00000147140 NONO ENSG00000157764 BRAF H. sapiens SSL Slorth 0.782858 View
ENSG00000157764 BRAF ENSG00000177565 TBL1XR1 H. sapiens SSL Slorth 0.78273 View
ENSG00000154710 RABGEF1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.782654 View
ENSG00000157764 BRAF ENSG00000158987 RAPGEF6 H. sapiens SSL Slorth 0.782325 View
ENSG00000105976 MET ENSG00000157764 BRAF H. sapiens SSL Slorth 0.782198 View
ENSG00000157764 BRAF ENSG00000185122 HSF1 H. sapiens SSL Slorth 0.782137 View
ENSG00000157764 BRAF ENSG00000204390 HSPA1L H. sapiens SSL Slorth 0.781972 View
ENSG00000157764 BRAF ENSG00000160551 TAOK1 H. sapiens SSL Slorth 0.781836 View
ENSG00000042753 AP2S1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.781684 View
ENSG00000157764 BRAF ENSG00000197323 TRIM33 H. sapiens SSL Slorth 0.781384 View
ENSG00000126803 HSPA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.781135 View
ENSG00000007944 MYLIP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.781119 View
ENSG00000141030 COPS3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.780806 View
ENSG00000082397 EPB41L3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.78061 View
ENSG00000157764 BRAF ENSG00000169756 LIMS1 H. sapiens SSL Slorth 0.780418 View
ENSG00000157764 BRAF ENSG00000185624 P4HB H. sapiens SSL Slorth 0.780219 View
ENSG00000157764 BRAF ENSG00000162337 LRP5 H. sapiens SSL Slorth 0.780161 View