BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.967234 View
ENSG00000135018 UBQLN1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.967126 View
ENSG00000157764 BRAF ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.966829 View
ENSG00000157764 BRAF ENSG00000169083 AR H. sapiens SDL Slorth 0.966796 View
ENSG00000072401 UBE2D1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.966754 View
ENSG00000145386 CCNA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.966601 View
ENSG00000157764 BRAF ENSG00000184937 WT1 H. sapiens SDL Slorth 0.966586 View
ENSG00000157764 BRAF ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.9665 View
ENSG00000157764 BRAF ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.966486 View
ENSG00000101146 RAE1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.966486 View
ENSG00000134086 VHL ENSG00000157764 BRAF H. sapiens SDL Slorth 0.966466 View
ENSG00000072062 PRKACA ENSG00000157764 BRAF H. sapiens SDL Slorth 0.966451 View
ENSG00000157764 BRAF ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.966428 View
ENSG00000157764 BRAF ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.96633 View
ENSG00000143799 PARP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.96627 View
ENSG00000157764 BRAF ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.966191 View
ENSG00000157764 BRAF ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.966168 View
ENSG00000085511 MAP3K4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.966113 View
ENSG00000157764 BRAF ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.965991 View
ENSG00000113721 PDGFRB ENSG00000157764 BRAF H. sapiens SDL Slorth 0.965954 View
ENSG00000124486 USP9X ENSG00000157764 BRAF H. sapiens SSL Slorth 0.965864 View
ENSG00000104365 IKBKB ENSG00000157764 BRAF H. sapiens SSL Slorth 0.96571 View
ENSG00000157764 BRAF ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.965691 View
ENSG00000080824 HSP90AA1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.965675 View
ENSG00000157764 BRAF ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.96564 View
ENSG00000097046 CDC7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.965622 View
ENSG00000157764 BRAF ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.965559 View
ENSG00000157764 BRAF ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.965559 View
ENSG00000135341 MAP3K7 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.965538 View
ENSG00000157764 BRAF ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.965492 View
ENSG00000157764 BRAF ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.965429 View
ENSG00000157764 BRAF ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.965411 View
ENSG00000099817 POLR2E ENSG00000157764 BRAF H. sapiens SSL Slorth 0.965385 View
ENSG00000094804 CDC6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.965329 View
ENSG00000157764 BRAF ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.96531 View
ENSG00000157764 BRAF ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.965274 View
ENSG00000157764 BRAF ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.965168 View
ENSG00000157764 BRAF ENSG00000170315 UBB H. sapiens SDL Slorth 0.96503 View
ENSG00000157764 BRAF ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.964957 View
ENSG00000157764 BRAF ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.964767 View