Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
BRAF
|
ENSG00000157764
|
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
|
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
|
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
|
lin-45 (C. elegans)
|
PRKCB
|
ENSG00000166501
|
adult T-cell lymphoma-leukaemia
|
No drugs in record
|
chromatin binding
protein serine/threonine kinase activity
protein kinase C activity
calcium-dependent protein kinase C activity
protein kinase C binding
calcium channel regulator activity
protein binding
ATP binding
zinc ion binding
ligand-dependent nuclear receptor transcription coactivator activity
histone kinase activity (H3-T6 specific)
histone binding
androgen receptor binding
|
PKC1 (S. cerevisiae)
pkc-2 (C. elegans)
inaC (D. melanogaster)
|