BRAF - HDAC2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
BRAF ENSG00000157764 melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)
HDAC2 ENSG00000196591

No diseases in record

BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
heat shock protein binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
sequence-specific DNA binding
NF-kappaB binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
RPD3 (S. cerevisiae)
hda-1 (C. elegans)
hda-3 (C. elegans)

References