TAF5 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF5	ENSG00000148835	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding transcription regulatory region DNA binding protein dimerization activity histone acetyltransferase activity ubiquitin binding protein complex scaffold activity chromatin binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly	TAF5 (S. cerevisiae) taf-5 (C. elegans) can (D. melanogaster) Taf5 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)