BRAF - MCM7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
MCM7	ENSG00000166508	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding DNA binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity chromatin binding DNA replication origin binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity single-stranded DNA-dependent ATPase activity hydrolase activity nucleotide binding ATP-dependent four-way junction helicase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM7 (S. cerevisiae) Mcm7 (D. melanogaster)