MAP2K4 - BRAF

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MAP2K4 ENSG00000065559 pancreatic
breast
colorectal

No drugs in record

protein kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
JUN kinase kinase activity
mitogen-activated protein kinase kinase kinase binding
PBS2 (S. cerevisiae)
sek-3 (C. elegans)
mkk-4 (C. elegans)
sek-6 (C. elegans)
Mkk4 (D. melanogaster)
BRAF ENSG00000157764 melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)