POLA1 - DHFR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
DHFR	ENSG00000228716	No diseases in record	METHOTREXATE PEMETREXED PRALATREXATE	mRNA binding dihydrofolate reductase activity folic acid binding drug binding folate reductase activity methotrexate binding NADPH binding protein binding NADP binding	DFR1 (S. cerevisiae)