TCF3 - SMAD3

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TCF3 ENSG00000071564 pre B-ALL

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
mitogen-activated protein kinase kinase kinase binding
enhancer binding
protein homodimerization activity
bHLH transcription factor binding
protein heterodimerization activity
repressing transcription factor binding
vitamin D response element binding
E-box binding
hlh-2 (C. elegans)
SMAD3 ENSG00000166949 colorectal carcinoma
oral squamous cell carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter proximal region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
collagen binding
beta-catenin binding
transcription factor binding
zinc ion binding
protein kinase binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
chromatin DNA binding
ubiquitin protein ligase binding
enhancer binding
identical protein binding
protein homodimerization activity
ubiquitin binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
co-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
sma-3 (C. elegans)
sma-2 (C. elegans)