POLA1 - PMS2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
POLA1 ENSG00000101868

No diseases in record

CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
protein kinase binding
metal ion binding
protein heterodimerization activity
4 iron, 4 sulfur cluster binding
DNA primase activity
POL1 (S. cerevisiae)
DNApol-alpha180 (D. melanogaster)
PMS2 ENSG00000122512 colorectal
endometrial
ovarian
medulloblastoma
glioma

No drugs in record

DNA binding
endonuclease activity
protein binding
ATP binding
ATPase activity
single base insertion or deletion binding
single-stranded DNA binding
MutSalpha complex binding
mismatched DNA binding
PMS1 (S. cerevisiae)
Pms2 (D. melanogaster)