MAP2K2 - AKT1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MAP2K2 ENSG00000126934 NSCLC
melanoma
TRAMETINIB
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
PDZ domain binding
protein serine/threonine kinase activator activity
metal ion binding
scaffold protein binding
PBS2 (S. cerevisiae)
mek-2 (C. elegans)
Dsor1 (D. melanogaster)
AKT1 ENSG00000142208 breast
colorectal
ovarian
NSCLC

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
kinase activity
enzyme binding
nitric-oxide synthase regulator activity
GTPase activating protein binding
identical protein binding
phosphatidylinositol-3,4-bisphosphate binding
protein phosphatase 2A binding
14-3-3 protein binding
phosphatidylinositol binding
SCH9 (S. cerevisiae)
YPK1 (S. cerevisiae)
YPK2 (S. cerevisiae)
akt-1 (C. elegans)
akt-2 (C. elegans)
Akt1 (D. melanogaster)