PMS1 - RAF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PMS1	ENSG00000064933	colorectal endometrial ovarian	No drugs in record	DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding	PMS1 (S. cerevisiae) pms-2 (C. elegans)
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)