RAF1 - HMGB1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
RAF1 ENSG00000132155 pilocytic astrocytoma
prostate
REGORAFENIB
SORAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
kinase activity
enzyme binding
mitogen-activated protein kinase kinase binding
identical protein binding
metal ion binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)
HMGB1 ENSG00000189403

No diseases in record

No drugs in record

four-way junction DNA binding
bubble DNA binding
lipopolysaccharide binding
phosphatidylserine binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
double-stranded RNA binding
single-stranded RNA binding
cytokine activity
protein binding
transcription factor binding
DNA binding, bending
calcium-dependent protein kinase regulator activity
lyase activity
C-X-C chemokine binding
protein kinase activator activity
chemoattractant activity
RAGE receptor binding
DNA polymerase binding
repressing transcription factor binding
supercoiled DNA binding
NHP6A (S. cerevisiae)
NHP6B (S. cerevisiae)
hmg-1.2 (C. elegans)