PIM1 - SMAD3

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PIM1 ENSG00000137193 NHL

No drugs in record

protein serine/threonine kinase activity
protein binding
ATP binding
transcription factor binding
manganese ion binding
ribosomal small subunit binding
mitochondrial light strand promoter anti-sense binding
serine-type peptidase activity
ATP-dependent peptidase activity
nucleotide binding
peptidase activity
single-stranded DNA binding
serine-type endopeptidase activity
hydrolase activity
DNA binding
Ran guanyl-nucleotide exchange factor activity
PSK1 (S. cerevisiae)
PSK2 (S. cerevisiae)
SMAD3 ENSG00000166949 colorectal carcinoma
oral squamous cell carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter proximal region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
collagen binding
beta-catenin binding
transcription factor binding
zinc ion binding
protein kinase binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
chromatin DNA binding
ubiquitin protein ligase binding
enhancer binding
identical protein binding
protein homodimerization activity
ubiquitin binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
co-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
sma-3 (C. elegans)
sma-2 (C. elegans)