CDK4 - IRS1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)