IRS1

ENSG00000169047 - H. sapiens

Pathways

Go term Description
GO:0004871 signal transducer activity
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005080 protein kinase C binding
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0042169 SH2 domain binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0000049 tRNA binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0005524 ATP binding
GO:0004822 isoleucine-tRNA ligase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
chico D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101266 CSNK2A1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.99006 View
ENSG00000091831 ESR1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989676 View
ENSG00000012048 BRCA1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989514 View
ENSG00000150991 UBC ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989414 View
ENSG00000116478 HDAC1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.989114 View
ENSG00000141510 TP53 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.988614 View
ENSG00000005339 CREBBP ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.985721 View
ENSG00000123374 CDK2 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.984778 View
ENSG00000100393 EP300 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.984415 View
ENSG00000132646 PCNA ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.984286 View
ENSG00000104365 IKBKB ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.983704 View
ENSG00000124181 PLCG1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.983301 View
ENSG00000136997 MYC ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.982677 View
ENSG00000164924 YWHAZ ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.98256 View
ENSG00000103275 UBE2I ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.982454 View
ENSG00000146648 EGFR ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.98219 View
ENSG00000097007 ABL1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.981556 View
ENSG00000139687 RB1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.981257 View
ENSG00000142208 AKT1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.980917 View
ENSG00000166949 SMAD3 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.980052 View
ENSG00000162385 MAGOH ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.979817 View
ENSG00000100644 HIF1A ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.978426 View
ENSG00000166913 YWHAB ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.978278 View
ENSG00000080824 HSP90AA1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.977249 View
ENSG00000096384 HSP90AB1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.977211 View
ENSG00000089159 PXN ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.977116 View
ENSG00000134086 VHL ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.976969 View
ENSG00000159352 PSMD4 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.975904 View
ENSG00000113721 PDGFRB ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.975266 View
ENSG00000116030 SUMO1 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.975128 View
ENSG00000109971 HSPA8 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.974877 View
ENSG00000162434 JAK1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.974865 View
ENSG00000132155 RAF1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.974757 View
ENSG00000102882 MAPK3 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.974456 View
ENSG00000100030 MAPK1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.974282 View
ENSG00000103275 UBE2I ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.974162 View
ENSG00000109670 FBXW7 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.973947 View
ENSG00000164305 CASP3 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.973197 View
ENSG00000169047 IRS1 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.972532 View
ENSG00000166949 SMAD3 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.97234 View