RAD16 - SIR2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD16	YBR114W	No diseases in record	No drugs in record	DNA-dependent ATPase activity metal ion binding damaged DNA binding helicase activity ATP binding zinc ion binding ubiquitin-protein transferase activity hydrolase activity nucleotide binding DNA binding protein binding single-stranded DNA endodeoxyribonuclease activity single-stranded DNA binding 3' overhang single-stranded DNA endodeoxyribonuclease activity	TTF2 (H. sapiens)
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)