SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDL042C SIR2 YHR090C YNG2 S. cerevisiae SSL BioGRID 2.0 View
YDL042C SIR2 YIL031W ULP2 S. cerevisiae SSL BioGRID 1.0 View
YOR209C NPT1 YDL042C SIR2 S. cerevisiae SSL BioGRID 1.0 View
YNL129W NRK1 YDL042C SIR2 S. cerevisiae SSL BioGRID 1.0 View
YBR009C HHF1 YDL042C SIR2 S. cerevisiae SDL BioGRID 1.0 View
YDL156W CMR1 YDL042C SIR2 S. cerevisiae SSL BioGRID 1.0 View
YDL042C SIR2 YJL194W CDC6 S. cerevisiae SDL Slorth 0.965407 View
YDL042C SIR2 YML032C RAD52 S. cerevisiae SDL Slorth 0.964847 View
YDL042C SIR2 YJL115W ASF1 S. cerevisiae SDL Slorth 0.964764 View
YDL042C SIR2 YNL330C RPD3 S. cerevisiae SDL Slorth 0.964265 View
YDL042C SIR2 YMR224C MRE11 S. cerevisiae SDL Slorth 0.963527 View
YBR010W HHT1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.963196 View
YDL042C SIR2 YGR252W GCN5 S. cerevisiae SDL Slorth 0.962592 View
YDL042C SIR2 YDR440W DOT1 S. cerevisiae SDL Slorth 0.961936 View
YDL042C SIR2 YDL140C RPO21 S. cerevisiae SDL Slorth 0.959733 View
YDL042C SIR2 YFR028C CDC14 S. cerevisiae SDL Slorth 0.957697 View
YDL042C SIR2 YNL021W HDA1 S. cerevisiae SDL Slorth 0.956739 View
YDL042C SIR2 YHR119W SET1 S. cerevisiae SDL Slorth 0.955885 View
YDL042C SIR2 YLR045C STU2 S. cerevisiae SDL Slorth 0.954493 View
YBR026C ETR1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.954299 View
YDL042C SIR2 YPR135W CTF4 S. cerevisiae SDL Slorth 0.953746 View
YDL042C SIR2 YOR244W ESA1 S. cerevisiae SDL Slorth 0.95347 View
YDL042C SIR2 YML032C RAD52 S. cerevisiae SSL Slorth 0.953224 View
YDL042C SIR2 YJL115W ASF1 S. cerevisiae SSL Slorth 0.953105 View
YDL042C SIR2 YNL021W HDA1 S. cerevisiae SSL Slorth 0.952976 View
YCR065W HCM1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.952968 View
YDL042C SIR2 YGR252W GCN5 S. cerevisiae SSL Slorth 0.952589 View
YDL042C SIR2 YNL031C HHT2 S. cerevisiae SDL Slorth 0.952546 View
YDL042C SIR2 YOL115W PAP2 S. cerevisiae SDL Slorth 0.95229 View
YDL042C SIR2 YNL030W HHF2 S. cerevisiae SDL Slorth 0.95199 View
YDL042C SIR2 YMR224C MRE11 S. cerevisiae SSL Slorth 0.951554 View
YBL088C TEL1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.950486 View
YDL042C SIR2 YJL074C SMC3 S. cerevisiae SDL Slorth 0.949709 View
YBR085W AAC3 YDL042C SIR2 S. cerevisiae SDL Slorth 0.949405 View
YDL042C SIR2 YLR032W RAD5 S. cerevisiae SDL Slorth 0.949217 View
YDL042C SIR2 YFR028C CDC14 S. cerevisiae SSL Slorth 0.948691 View
YDL042C SIR2 YGR274C TAF1 S. cerevisiae SDL Slorth 0.947632 View
YBR231C SWC5 YDL042C SIR2 S. cerevisiae SSL Slorth 0.947575 View
YCR094W CDC50 YDL042C SIR2 S. cerevisiae SDL Slorth 0.947551 View
YDL042C SIR2 YHR119W SET1 S. cerevisiae SSL Slorth 0.94748 View