SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDL042C SIR2 YDL102W POL3 S. cerevisiae SDL Slorth 0.916999 View
YDL042C SIR2 YOL004W SIN3 S. cerevisiae SDL Slorth 0.916967 View
YDL042C SIR2 YGR270W YTA7 S. cerevisiae SSL Slorth 0.916737 View
YDL042C SIR2 YHL031C GOS1 S. cerevisiae SDL Slorth 0.916514 View
YDL042C SIR2 YKL213C DOA1 S. cerevisiae SDL Slorth 0.916496 View
YDL042C SIR2 YGL201C MCM6 S. cerevisiae SDL Slorth 0.916457 View
YDL042C SIR2 YLR113W HOG1 S. cerevisiae SDL Slorth 0.916452 View
YDL042C SIR2 YKL139W CTK1 S. cerevisiae SSL Slorth 0.916126 View
YDL042C SIR2 YER095W RAD51 S. cerevisiae SSL Slorth 0.915646 View
YDL042C SIR2 YGR108W CLB1 S. cerevisiae SDL Slorth 0.915415 View
YDL042C SIR2 YNL248C RPA49 S. cerevisiae SSL Slorth 0.91525 View
YDL042C SIR2 YPL153C RAD53 S. cerevisiae SSL Slorth 0.915207 View
YDL042C SIR2 YGL043W DST1 S. cerevisiae SSL Slorth 0.914882 View
YDL042C SIR2 YLR399C BDF1 S. cerevisiae SSL Slorth 0.914295 View
YDL042C SIR2 YGL003C CDH1 S. cerevisiae SSL Slorth 0.914241 View
YDL017W CDC7 YDL042C SIR2 S. cerevisiae SSL Slorth 0.913749 View
YDL042C SIR2 YFL039C ACT1 S. cerevisiae SDL Slorth 0.913576 View
YDL042C SIR2 YJL176C SWI3 S. cerevisiae SSL Slorth 0.912962 View
YDL042C SIR2 YER095W RAD51 S. cerevisiae SDL Slorth 0.912717 View
YDL042C SIR2 YPR019W MCM4 S. cerevisiae SDL Slorth 0.91266 View
YBR041W FAT1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.912165 View
YBR135W CKS1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.911892 View
YDL042C SIR2 YLR103C CDC45 S. cerevisiae SDL Slorth 0.911711 View
YDL042C SIR2 YGR056W RSC1 S. cerevisiae SSL Slorth 0.91151 View
YDL042C SIR2 YIL150C MCM10 S. cerevisiae SSL Slorth 0.911426 View
YDL042C SIR2 YLR383W SMC6 S. cerevisiae SDL Slorth 0.911254 View
YDL042C SIR2 YGL058W RAD6 S. cerevisiae SSL Slorth 0.911096 View
YBR274W CHK1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.91099 View
YDL042C SIR2 YNL139C THO2 S. cerevisiae SDL Slorth 0.910798 View
YBR010W HHT1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.910695 View
YBR223C TDP1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.910571 View
YBR114W RAD16 YDL042C SIR2 S. cerevisiae SDL Slorth 0.910313 View
YDL042C SIR2 YDL140C RPO21 S. cerevisiae SSL Slorth 0.910159 View
YDL042C SIR2 YGR092W DBF2 S. cerevisiae SDL Slorth 0.909907 View
YDL042C SIR2 YML064C TEM1 S. cerevisiae SDL Slorth 0.909074 View
YDL042C SIR2 YLR357W RSC2 S. cerevisiae SSL Slorth 0.908635 View
YDL042C SIR2 YGR098C ESP1 S. cerevisiae SDL Slorth 0.90854 View
YAL032C PRP45 YDL042C SIR2 S. cerevisiae SDL Slorth 0.908091 View
YDL042C SIR2 YLR396C VPS33 S. cerevisiae SDL Slorth 0.907511 View
YDL042C SIR2 YDL116W NUP84 S. cerevisiae SDL Slorth 0.907425 View