SIR2 - CTK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
CTK1	YKL139W	No diseases in record	No drugs in record	cyclin-dependent protein serine/threonine kinase activity cyclin binding transcription factor binding transferase activity ATP binding protein kinase activity protein serine/threonine kinase activity kinase activity RNA polymerase II carboxy-terminal domain kinase activity transcription regulatory region DNA binding nucleotide binding	CDK12 (H. sapiens) CDK9 (H. sapiens) CDK13 (H. sapiens)