SIR2 - RAD27

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
RAD27	YKL113C	No diseases in record	No drugs in record	catalytic activity DNA binding nuclease activity 5'-flap endonuclease activity hydrolase activity metal ion binding exonuclease activity endonuclease activity 5'-3' exonuclease activity hydrolase activity, acting on ester bonds	FEN1 (H. sapiens) GEN1 (H. sapiens)