MLH1

ENSG00000076242 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0032137 guanine/thymine mispair binding
GO:0003697 single-stranded DNA binding
GO:0032407 MutSalpha complex binding
GO:0030983 mismatched DNA binding
GO:0000404 heteroduplex DNA loop binding
GO:0032135 DNA insertion or deletion binding
GO:0032139 dinucleotide insertion or deletion binding
GO:0003690 double-stranded DNA binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
endometrial
ovarian
CNS tumours
CNS

Orthologs

Gene Organism
MLH1 S. cerevisiae
Mlh1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000012048 BRCA1 ENSG00000076242 MLH1 H. sapiens SDL Slorth 0.987408 View
ENSG00000076242 MLH1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.976719 View
ENSG00000002016 RAD52 ENSG00000076242 MLH1 H. sapiens SDL Slorth 0.975583 View
ENSG00000076242 MLH1 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.973046 View
ENSG00000076242 MLH1 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.971554 View
ENSG00000076242 MLH1 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.970111 View
ENSG00000076242 MLH1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.96897 View
ENSG00000076242 MLH1 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.963126 View
ENSG00000076242 MLH1 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.961973 View
ENSG00000076242 MLH1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.960168 View
ENSG00000076242 MLH1 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.959861 View
ENSG00000076242 MLH1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.95767 View
ENSG00000076242 MLH1 ENSG00000109670 FBXW7 H. sapiens SSL Slorth 0.95418 View
ENSG00000076242 MLH1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.951821 View
ENSG00000076242 MLH1 ENSG00000100297 MCM5 H. sapiens SSL Slorth 0.950299 View
ENSG00000076242 MLH1 ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.949622 View
ENSG00000076242 MLH1 ENSG00000149273 RPS3 H. sapiens SDL Slorth 0.947448 View
ENSG00000076242 MLH1 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.947448 View
ENSG00000076242 MLH1 ENSG00000080503 SMARCA2 H. sapiens SSL Slorth 0.947411 View
ENSG00000012048 BRCA1 ENSG00000076242 MLH1 H. sapiens SSL Slorth 0.947049 View
ENSG00000076242 MLH1 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.947028 View
ENSG00000076242 MLH1 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.946818 View
ENSG00000076242 MLH1 ENSG00000092201 SUPT16H H. sapiens SSL Slorth 0.946687 View
ENSG00000076242 MLH1 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.946495 View
ENSG00000076242 MLH1 ENSG00000104738 MCM4 H. sapiens SSL Slorth 0.945623 View
ENSG00000076242 MLH1 ENSG00000105325 FZR1 H. sapiens SSL Slorth 0.945173 View
ENSG00000076242 MLH1 ENSG00000105173 CCNE1 H. sapiens SSL Slorth 0.945141 View
ENSG00000076242 MLH1 ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.944498 View
ENSG00000076242 MLH1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.94378 View
ENSG00000076242 MLH1 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.943178 View
ENSG00000076242 MLH1 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.943073 View
ENSG00000076242 MLH1 ENSG00000101665 SMAD7 H. sapiens SSL Slorth 0.943006 View
ENSG00000076242 MLH1 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.942997 View
ENSG00000076242 MLH1 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.942988 View
ENSG00000076242 MLH1 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.942684 View
ENSG00000076242 MLH1 ENSG00000102054 RBBP7 H. sapiens SSL Slorth 0.942192 View
ENSG00000076242 MLH1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.941176 View
ENSG00000076242 MLH1 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.941093 View
ENSG00000076242 MLH1 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.940589 View
ENSG00000005339 CREBBP ENSG00000076242 MLH1 H. sapiens SSL Slorth 0.94055 View