TOP3B

ENSG00000100038 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
GO:0003917 DNA topoisomerase type I activity
GO:0005515 protein binding

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
TOP3 S. cerevisiae
Y48C3A.14 C. elegans
Top3beta D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000100038 TOP3B ENSG00000100393 EP300 H. sapiens SDL Slorth 0.982162 View
ENSG00000100038 TOP3B ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.981039 View
ENSG00000100038 TOP3B ENSG00000132646 PCNA H. sapiens SDL Slorth 0.980994 View
ENSG00000100038 TOP3B ENSG00000141510 TP53 H. sapiens SDL Slorth 0.980828 View
ENSG00000100038 TOP3B ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.979681 View
ENSG00000100038 TOP3B ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.978962 View
ENSG00000100038 TOP3B ENSG00000150991 UBC H. sapiens SDL Slorth 0.97258 View
ENSG00000100038 TOP3B ENSG00000133703 KRAS H. sapiens SSL Slorth 0.970912 View
ENSG00000100038 TOP3B ENSG00000146648 EGFR H. sapiens SDL Slorth 0.963828 View
ENSG00000100038 TOP3B ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.961943 View
ENSG00000100038 TOP3B ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.961931 View
ENSG00000100038 TOP3B ENSG00000197122 SRC H. sapiens SDL Slorth 0.959619 View
ENSG00000100038 TOP3B ENSG00000169083 AR H. sapiens SDL Slorth 0.952365 View
ENSG00000100038 TOP3B ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.948661 View
ENSG00000097046 CDC7 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.944707 View
ENSG00000100038 TOP3B ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.942135 View
ENSG00000004700 RECQL ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.942002 View
ENSG00000100038 TOP3B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.941774 View
ENSG00000100038 TOP3B ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.938369 View
ENSG00000100038 TOP3B ENSG00000139687 RB1 H. sapiens SDL Slorth 0.935538 View
ENSG00000100038 TOP3B ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.919256 View
ENSG00000100038 TOP3B ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.916199 View
ENSG00000082701 GSK3B ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.915879 View
ENSG00000100038 TOP3B ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.902943 View
ENSG00000100038 TOP3B ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.901585 View
ENSG00000010810 FYN ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.896327 View
ENSG00000100038 TOP3B ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.890687 View
ENSG00000097007 ABL1 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.887815 View
ENSG00000094804 CDC6 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.886287 View
ENSG00000012048 BRCA1 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.871534 View
ENSG00000069869 NEDD4 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.868334 View
ENSG00000070010 UFD1L ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.85807 View
ENSG00000082898 XPO1 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.855037 View
ENSG00000096968 JAK2 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.852124 View
ENSG00000005339 CREBBP ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.8505 View
ENSG00000100038 TOP3B ENSG00000176105 YES1 H. sapiens SSL Slorth 0.846539 View
ENSG00000062822 POLD1 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.845176 View
ENSG00000049759 NEDD4L ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.844864 View
ENSG00000004897 CDC27 ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.842014 View
ENSG00000078747 ITCH ENSG00000100038 TOP3B H. sapiens SSL Slorth 0.840563 View