ITK

ENSG00000113263 - H. sapiens

Pathways

Go term Description
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
peripheral T-cell lymphoma

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.986354 View
ENSG00000012048 BRCA1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.98518 View
ENSG00000110395 CBL ENSG00000113263 ITK H. sapiens SDL Slorth 0.984231 View
ENSG00000100393 EP300 ENSG00000113263 ITK H. sapiens SDL Slorth 0.98343 View
ENSG00000005339 CREBBP ENSG00000113263 ITK H. sapiens SDL Slorth 0.981425 View
ENSG00000113263 ITK ENSG00000133703 KRAS H. sapiens SSL Slorth 0.981403 View
ENSG00000010810 FYN ENSG00000113263 ITK H. sapiens SDL Slorth 0.981383 View
ENSG00000109670 FBXW7 ENSG00000113263 ITK H. sapiens SSL Slorth 0.979745 View
ENSG00000097007 ABL1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.979634 View
ENSG00000113263 ITK ENSG00000150991 UBC H. sapiens SDL Slorth 0.977484 View
ENSG00000080824 HSP90AA1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.976679 View
ENSG00000113263 ITK ENSG00000141510 TP53 H. sapiens SDL Slorth 0.975151 View
ENSG00000113263 ITK ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.973015 View
ENSG00000100030 MAPK1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.970013 View
ENSG00000113263 ITK ENSG00000124181 PLCG1 H. sapiens SDL Slorth 0.966799 View
ENSG00000113263 ITK ENSG00000197122 SRC H. sapiens SDL Slorth 0.966524 View
ENSG00000101266 CSNK2A1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.965073 View
ENSG00000113263 ITK ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.962367 View
ENSG00000055130 CUL1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.959416 View
ENSG00000113263 ITK ENSG00000121774 KHDRBS1 H. sapiens SDL Slorth 0.9589 View
ENSG00000113263 ITK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.955317 View
ENSG00000105640 RPL18A ENSG00000113263 ITK H. sapiens SDL Slorth 0.953861 View
ENSG00000108298 RPL19 ENSG00000113263 ITK H. sapiens SDL Slorth 0.95285 View
ENSG00000113263 ITK ENSG00000158092 NCK1 H. sapiens SDL Slorth 0.952455 View
ENSG00000113263 ITK ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.951963 View
ENSG00000071082 RPL31 ENSG00000113263 ITK H. sapiens SDL Slorth 0.950653 View
ENSG00000087191 PSMC5 ENSG00000113263 ITK H. sapiens SDL Slorth 0.950157 View
ENSG00000105372 RPS19 ENSG00000113263 ITK H. sapiens SDL Slorth 0.946468 View
ENSG00000113263 ITK ENSG00000182866 LCK H. sapiens SDL Slorth 0.946073 View
ENSG00000097007 ABL1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.945842 View
ENSG00000101146 RAE1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.945756 View
ENSG00000097046 CDC7 ENSG00000113263 ITK H. sapiens SSL Slorth 0.943967 View
ENSG00000103275 UBE2I ENSG00000113263 ITK H. sapiens SDL Slorth 0.943808 View
ENSG00000089157 RPLP0 ENSG00000113263 ITK H. sapiens SDL Slorth 0.942493 View
ENSG00000113263 ITK ENSG00000146648 EGFR H. sapiens SDL Slorth 0.941951 View
ENSG00000100028 SNRPD3 ENSG00000113263 ITK H. sapiens SDL Slorth 0.941856 View
ENSG00000096968 JAK2 ENSG00000113263 ITK H. sapiens SDL Slorth 0.941514 View
ENSG00000108671 PSMD11 ENSG00000113263 ITK H. sapiens SDL Slorth 0.940573 View
ENSG00000110107 PRPF19 ENSG00000113263 ITK H. sapiens SDL Slorth 0.939515 View
ENSG00000050820 BCAR1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.937891 View