RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000165731 RET H. sapiens SDL Slorth 0.907933 View
ENSG00000161057 PSMC2 ENSG00000165731 RET H. sapiens SDL Slorth 0.907342 View
ENSG00000165731 RET ENSG00000183741 CBX6 H. sapiens SDL Slorth 0.907316 View
ENSG00000002016 RAD52 ENSG00000165731 RET H. sapiens SSL Slorth 0.906622 View
ENSG00000165731 RET ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.906488 View
ENSG00000165731 RET ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.906361 View
ENSG00000141968 VAV1 ENSG00000165731 RET H. sapiens SDL Slorth 0.906329 View
ENSG00000105976 MET ENSG00000165731 RET H. sapiens SDL Slorth 0.906191 View
ENSG00000112658 SRF ENSG00000165731 RET H. sapiens SSL Slorth 0.905966 View
ENSG00000149273 RPS3 ENSG00000165731 RET H. sapiens SDL Slorth 0.905911 View
ENSG00000165731 RET ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.905836 View
ENSG00000107581 EIF3A ENSG00000165731 RET H. sapiens SSL Slorth 0.905722 View
ENSG00000068078 FGFR3 ENSG00000165731 RET H. sapiens SSL Slorth 0.9055 View
ENSG00000106355 LSM5 ENSG00000165731 RET H. sapiens SSL Slorth 0.90534 View
ENSG00000165731 RET ENSG00000171634 BPTF H. sapiens SDL Slorth 0.905318 View
ENSG00000165731 RET ENSG00000175104 TRAF6 H. sapiens SSL Slorth 0.905309 View
ENSG00000135341 MAP3K7 ENSG00000165731 RET H. sapiens SDL Slorth 0.905213 View
ENSG00000123358 NR4A1 ENSG00000165731 RET H. sapiens SSL Slorth 0.904922 View
ENSG00000165731 RET ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.904362 View
ENSG00000115694 STK25 ENSG00000165731 RET H. sapiens SSL Slorth 0.904158 View
ENSG00000165731 RET ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.903818 View
ENSG00000165731 RET ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.903802 View
ENSG00000143190 POU2F1 ENSG00000165731 RET H. sapiens SSL Slorth 0.903685 View
ENSG00000165731 RET ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.903627 View
ENSG00000114767 RRP9 ENSG00000165731 RET H. sapiens SSL Slorth 0.903451 View
ENSG00000165731 RET ENSG00000169220 RGS14 H. sapiens SDL Slorth 0.903274 View
ENSG00000165731 RET ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.903184 View
ENSG00000150093 ITGB1 ENSG00000165731 RET H. sapiens SDL Slorth 0.903168 View
ENSG00000080503 SMARCA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.90316 View
ENSG00000085840 ORC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.90259 View
ENSG00000088986 DYNLL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.902583 View
ENSG00000111276 CDKN1B ENSG00000165731 RET H. sapiens SSL Slorth 0.902542 View
ENSG00000135521 LTV1 ENSG00000165731 RET H. sapiens SSL Slorth 0.902503 View
ENSG00000153071 DAB2 ENSG00000165731 RET H. sapiens SDL Slorth 0.902217 View
ENSG00000044574 HSPA5 ENSG00000165731 RET H. sapiens SSL Slorth 0.902122 View
ENSG00000139687 RB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.902052 View
ENSG00000132326 PER2 ENSG00000165731 RET H. sapiens SSL Slorth 0.902002 View
ENSG00000080986 NDC80 ENSG00000165731 RET H. sapiens SSL Slorth 0.901824 View
ENSG00000077782 FGFR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.901614 View
ENSG00000140464 PML ENSG00000165731 RET H. sapiens SSL Slorth 0.901032 View